HIV-1 WHOLE GENOME

HIV-1 WHOLE GENOME is a qualitative device based on RT-PCR amplification of the entire genome of the virus. In addition to the known resistance regions (PR, RT, IN, V3LOOP) it is possible to identify mutations present on important viral genomic regions such as: the group-specific antigen “gag”, the viral infectivity factor “vif”, the accessory protein “nef” and the regions adjacent to integrase.

Following amplification, sequencing in Next Generation Sequencing (NGS) allows the genotyping of the virus and the evaluation of genomic mutations.

This product can be used as a diagnostic aid to investigate viral mutations present in HIV-1 positive patients

After sequencing, the samples are automatically analyzed by using a dedicated software which, by querying the common databases, returns a report with all the mutations associated with the HIV-1 virus.